diff --git a/package/grpc/0001-CMakeLists.txt-fix-cross-compilation-with-gRPC_BUILD.patch b/package/grpc/0001-CMakeLists.txt-fix-cross-compilation-with-gRPC_BUILD.patch
new file mode 100644
index 0000000000..553be8cb99
--- /dev/null
+++ b/package/grpc/0001-CMakeLists.txt-fix-cross-compilation-with-gRPC_BUILD.patch
@@ -0,0 +1,43 @@
+From 268815d74ea34856c686dce9e9c23106b51f2782 Mon Sep 17 00:00:00 2001
+From: Thomas De Schampheleire <thomas.de_schampheleire@nokia.com>
+Date: Tue, 2 Feb 2021 21:46:29 +0100
+Subject: [PATCH] CMakeLists.txt: fix cross-compilation with
+ gRPC_BUILD_GRPC_CPP_PLUGIN=OFF
+
+When cross-compiling gRPC, a native version of 'grpc_cpp_plugin' is searched
+in the environment. For most use cases, a cross version of this file is not
+needed.
+
+However, when cross-building with -DgRPC_BUILD_GRPC_CPP_PLUGIN=OFF, there
+are some build errors, for example:
+
+make[3]: *** No rule to make target 'grpc_cpp_plugin', needed by 'gens/src/proto/grpc/reflection/v1alpha/reflection.grpc.pb.cc'.  Stop.
+
+This is because there is still a hard dependency on 'grpc_cpp_plugin' for
+these targets, not taking into account the cross-compilation case.
+
+Fix by depending on the variable gRPC_CPP_PLUGIN, which is set correctly for
+either cross or native case.
+
+Signed-off-by: Thomas De Schampheleire <thomas.de_schampheleire@nokia.com>
+
+---
+ CMakeLists.txt | 2 +-
+ 1 file changed, 1 insertion(+), 1 deletion(-)
+
+diff --git a/CMakeLists.txt b/CMakeLists.txt
+index 6bdae22083..08aea609f7 100644
+--- a/CMakeLists.txt
++++ b/CMakeLists.txt
+@@ -317,7 +317,7 @@ function(protobuf_generate_grpc_cpp)
+            --plugin=protoc-gen-grpc=${_gRPC_CPP_PLUGIN}
+            ${_protobuf_include_path}
+            ${REL_FIL}
+-      DEPENDS ${ABS_FIL} ${_gRPC_PROTOBUF_PROTOC} grpc_cpp_plugin
++      DEPENDS ${ABS_FIL} ${_gRPC_PROTOBUF_PROTOC} ${_gRPC_CPP_PLUGIN}
+       WORKING_DIRECTORY ${CMAKE_CURRENT_SOURCE_DIR}
+       COMMENT "Running gRPC C++ protocol buffer compiler on ${FIL}"
+       VERBATIM)
+-- 
+2.26.2
+