diff --git a/package/gcc/gcc.mk b/package/gcc/gcc.mk
index 3719bfb004..114e774503 100644
--- a/package/gcc/gcc.mk
+++ b/package/gcc/gcc.mk
@@ -142,6 +142,12 @@ ifeq ($(BR2_mips64)$(BR2_mips64el):$(BR2_MIPS_NABI32),y:y)
 HOST_GCC_COMMON_CONF_OPTS += --disable-libsanitizer
 endif
 
+# libsanitizer bundled in gcc 12 fails to build for mips32 due to
+# mixing kernel and user struct stat.
+ifeq ($(BR2_mips)$(BR2_mipsel):$(BR2_TOOLCHAIN_GCC_AT_LEAST_12),y:y)
+HOST_GCC_COMMON_CONF_OPTS += --disable-libsanitizer
+endif
+
 # The logic in libbacktrace/configure.ac to detect if __sync builtins
 # are available assumes they are as soon as target_subdir is not
 # empty, i.e when cross-compiling. However, some platforms do not have