diff --git a/package/qemu/qemu.mk b/package/qemu/qemu.mk
index 470c285f16..50ace104ce 100644
--- a/package/qemu/qemu.mk
+++ b/package/qemu/qemu.mk
@@ -56,6 +56,12 @@ endif
 
 endif
 
+ifeq ($(BR2_TOOLCHAIN_USES_UCLIBC),y)
+QEMU_OPTS += --disable-vhost-user
+else
+QEMU_OPTS += --enable-vhost-user
+endif
+
 ifeq ($(BR2_PACKAGE_QEMU_SLIRP),y)
 QEMU_OPTS += --enable-slirp=system
 QEMU_DEPENDENCIES += slirp