diff --git a/package/python-httpx/Config.in b/package/python-httpx/Config.in
index 592cd559cd..0d20e6ca06 100644
--- a/package/python-httpx/Config.in
+++ b/package/python-httpx/Config.in
@@ -4,7 +4,6 @@ config BR2_PACKAGE_PYTHON_HTTPX
 	select BR2_PACKAGE_PYTHON_CERTIFI # runtime
 	select BR2_PACKAGE_PYTHON_HTTPCORE # runtime
 	select BR2_PACKAGE_PYTHON_IDNA # runtime
-	select BR2_PACKAGE_PYTHON_SNIFFIO # runtime
 	help
 	  The next generation HTTP client.
 
diff --git a/package/python-httpx/python-httpx.hash b/package/python-httpx/python-httpx.hash
index 3ffd491c9e..b2609c9b5c 100644
--- a/package/python-httpx/python-httpx.hash
+++ b/package/python-httpx/python-httpx.hash
@@ -1,5 +1,5 @@
 # md5, sha256 from https://pypi.org/pypi/httpx/json
-md5  f29763f29da610b185d2ca33937c572f  httpx-0.27.2.tar.gz
-sha256  f7c2be1d2f3c3c3160d441802406b206c2b76f5947b11115e6df10c6c65e66c2  httpx-0.27.2.tar.gz
+md5  774cf32b9cd94a44189fbe5871026664  httpx-0.28.1.tar.gz
+sha256  75e98c5f16b0f35b567856f597f06ff2270a374470a5c2392242528e3e3e42fc  httpx-0.28.1.tar.gz
 # Locally computed sha256 checksums
 sha256  4ec59d544f12b5f539a3a716fd321ac58ccd8030b465221f2c880200cdf28d8d  LICENSE.md
diff --git a/package/python-httpx/python-httpx.mk b/package/python-httpx/python-httpx.mk
index 21bbd48a58..aef46a33bf 100644
--- a/package/python-httpx/python-httpx.mk
+++ b/package/python-httpx/python-httpx.mk
@@ -4,9 +4,9 @@
 #
 ################################################################################
 
-PYTHON_HTTPX_VERSION = 0.27.2
+PYTHON_HTTPX_VERSION = 0.28.1
 PYTHON_HTTPX_SOURCE = httpx-$(PYTHON_HTTPX_VERSION).tar.gz
-PYTHON_HTTPX_SITE = https://files.pythonhosted.org/packages/78/82/08f8c936781f67d9e6b9eeb8a0c8b4e406136ea4c3d1f89a5db71d42e0e6
+PYTHON_HTTPX_SITE = https://files.pythonhosted.org/packages/b1/df/48c586a5fe32a0f01324ee087459e112ebb7224f646c0b5023f5e79e9956
 PYTHON_HTTPX_SETUP_TYPE = hatch
 PYTHON_HTTPX_LICENSE = BSD-3-Clause
 PYTHON_HTTPX_LICENSE_FILES = LICENSE.md