diff --git a/package/guile/guile.mk b/package/guile/guile.mk
index c74325252f..0f245fca76 100644
--- a/package/guile/guile.mk
+++ b/package/guile/guile.mk
@@ -64,7 +64,6 @@ GUILE_CONF_ENV += GUILE_FOR_BUILD=$(HOST_DIR)/bin/guile \
 	CFLAGS="$(TARGET_CFLAGS) $(GUILE_CFLAGS)"
 
 GUILE_CONF_OPTS += \
-	--with-libltdl-prefix=$(STAGING_DIR)/usr/lib \
 	--with-libgmp-prefix=$(STAGING_DIR)/usr/lib \
 	--with-libunistring-prefix=$(STAGING_DIR)/usr/lib