diff --git a/package/mesa3d/Config.in b/package/mesa3d/Config.in
index 8cdb548fb6..32d13bc747 100644
--- a/package/mesa3d/Config.in
+++ b/package/mesa3d/Config.in
@@ -253,6 +253,7 @@ config BR2_PACKAGE_MESA3D_GALLIUM_DRIVER_RADEONSI
 	depends on BR2_USE_MMU # libdrm
 	depends on BR2_i386 || BR2_x86_64
 	select BR2_PACKAGE_MESA3D_GALLIUM_DRIVER
+	select BR2_PACKAGE_MESA3D_HOST_NATIVE_CONTEXT_SUPPORTED_DRIVER
 	select BR2_PACKAGE_LIBDRM_AMDGPU
 	select BR2_PACKAGE_LIBDRM_RADEON
 	select BR2_PACKAGE_LLVM_AMDGPU if BR2_PACKAGE_MESA3D_LLVM
@@ -345,6 +346,7 @@ config BR2_PACKAGE_MESA3D_VULKAN_DRIVER_AMD
 	depends on BR2_TOOLCHAIN_HAS_SYNC_4 || !BR2_PACKAGE_XORG7 # libxshmfence
 	select BR2_PACKAGE_LIBDRM_AMDGPU
 	select BR2_PACKAGE_LLVM_AMDGPU if BR2_PACKAGE_MESA3D_LLVM
+	select BR2_PACKAGE_MESA3D_HOST_NATIVE_CONTEXT_SUPPORTED_DRIVER
 	select BR2_PACKAGE_MESA3D_VULKAN_DRIVER
 	help
 	  RADV is a userspace driver that implements the
@@ -419,6 +421,23 @@ config BR2_PACKAGE_MESA3D_VULKAN_DRIVER_VIRTIO
 	help
 	  Vulkan VirtIO (venus) driver.
 
+comment "Host native context drivers"
+	depends on BR2_PACKAGE_MESA3D_HOST_NATIVE_CONTEXT_SUPPORTED_DRIVER
+
+config BR2_PACKAGE_MESA3D_HOST_NATIVE_CONTEXT_DRIVER_AMDGPU
+	bool "amdgpu-virtio"
+	depends on BR2_PACKAGE_MESA3D_GALLIUM_DRIVER_RADEONSI || \
+		BR2_PACKAGE_MESA3D_VULKAN_DRIVER_AMD
+	help
+	  Enable VirtIO support for AMDGPU native contexts
+	  used by the radeonsi (OpenGL) and RADV (Vulkan) drivers.
+
+	  Select this when running Mesa inside a virtual machine
+	  with virtio-gpu host native context support.
+
+config BR2_PACKAGE_MESA3D_HOST_NATIVE_CONTEXT_SUPPORTED_DRIVER
+	bool
+
 if BR2_PACKAGE_MESA3D_DRIVER
 
 comment "OpenGL API Support"
diff --git a/package/mesa3d/mesa3d.mk b/package/mesa3d/mesa3d.mk
index 1eaa4c577e..34597966af 100644
--- a/package/mesa3d/mesa3d.mk
+++ b/package/mesa3d/mesa3d.mk
@@ -151,6 +151,12 @@ ifeq ($(BR2_PACKAGE_MESA3D_GALLIUM_DRIVER_ETNAVIV),y)
 MESA3D_DEPENDENCIES += host-python-pycparser
 endif
 
+ifeq ($(BR2_PACKAGE_MESA3D_HOST_NATIVE_CONTEXT_DRIVER_AMDGPU),y)
+MESA3D_CONF_OPTS += -Damdgpu-virtio=true
+else
+MESA3D_CONF_OPTS += -Damdgpu-virtio=false
+endif
+
 ifeq ($(BR2_PACKAGE_MESA3D_VULKAN_DRIVER_INTEL),y)
 MESA3D_DEPENDENCIES += host-python-ply
 endif