diff --git a/package/python-libusb1/Config.in b/package/python-libusb1/Config.in
index e464a0394d..fbad70c375 100644
--- a/package/python-libusb1/Config.in
+++ b/package/python-libusb1/Config.in
@@ -1,5 +1,6 @@
 config BR2_PACKAGE_PYTHON_LIBUSB1
 	bool "python-libusb1"
+	depends on BR2_PACKAGE_PYTHON3
 	depends on BR2_TOOLCHAIN_HAS_THREADS # libusb
 	depends on BR2_TOOLCHAIN_GCC_AT_LEAST_4_9 # libusb
 	select BR2_PACKAGE_LIBUSB
@@ -9,5 +10,6 @@ config BR2_PACKAGE_PYTHON_LIBUSB1
 	  http://github.com/vpelletier/python-libusb1
 
 comment "python-libusb1 needs a toolchain w/ threads, gcc >= 4.9"
+	depends on BR2_PACKAGE_PYTHON3
 	depends on !BR2_TOOLCHAIN_HAS_THREADS || \
 		!BR2_TOOLCHAIN_GCC_AT_LEAST_4_9