diff --git a/package/python-bluezero/Config.in b/package/python-bluezero/Config.in
index 3a9e5df6b7..7126b3ca50 100644
--- a/package/python-bluezero/Config.in
+++ b/package/python-bluezero/Config.in
@@ -1,5 +1,8 @@
 config BR2_PACKAGE_PYTHON_BLUEZERO
 	bool "python-bluezero"
+	depends on BR2_PACKAGE_GOBJECT_INTROSPECTION_ARCH_SUPPORTS # python-gobject -> gobject-introspection
+	depends on BR2_TOOLCHAIN_GCC_AT_LEAST_4_9 # python-gobject -> gobject-introspection
+	depends on BR2_TOOLCHAIN_USES_GLIBC # python-gobject -> gobject-introspection
 	depends on BR2_PACKAGE_PYTHON3
 	select BR2_PACKAGE_DBUS_PYTHON # runtime
 	select BR2_PACKAGE_PYTHON_GOBJECT # runtime
@@ -7,3 +10,9 @@ config BR2_PACKAGE_PYTHON_BLUEZERO
 	  Python library for Bluetooth Low Energy (BLE) on Linux.
 
 	  https://github.com/ukBaz/python-bluezero
+
+comment "python-bluezero needs a glibc toolchain, gcc >= 4.9"
+	depends on BR2_PACKAGE_PYTHON3
+	depends on BR2_PACKAGE_GOBJECT_INTROSPECTION_ARCH_SUPPORTS
+	depends on !BR2_TOOLCHAIN_USES_GLIBC || \
+		!BR2_TOOLCHAIN_GCC_AT_LEAST_4_9