diff --git a/package/libiio/libiio.mk b/package/libiio/libiio.mk
index 4ce933a0cd..f706298c22 100644
--- a/package/libiio/libiio.mk
+++ b/package/libiio/libiio.mk
@@ -17,6 +17,12 @@ LIBIIO_CONF_OPTS = -DENABLE_IPV6=ON \
 	-DWITH_TESTS=$(if $(BR2_PACKAGE_LIBIIO_TESTS),ON,OFF) \
 	-DWITH_DOC=OFF
 
+ifeq ($(BR2_TOOLCHAIN_HAS_THREADS),y)
+LIBIIO_CONF_OPTS += -DNO_THREADS=OFF
+else
+LIBIIO_CONF_OPTS += -DNO_THREADS=ON
+endif
+
 ifeq ($(BR2_PACKAGE_LIBIIO_XML_BACKEND),y)
 LIBIIO_DEPENDENCIES += libxml2
 LIBIIO_CONF_OPTS += -DWITH_XML_BACKEND=ON