diff --git a/package/libde265/libde265.mk b/package/libde265/libde265.mk
index d7e3df83ca..b559a9f607 100644
--- a/package/libde265/libde265.mk
+++ b/package/libde265/libde265.mk
@@ -16,4 +16,8 @@ ifeq ($(BR2_TOOLCHAIN_HAS_LIBATOMIC),y)
 LIBDE265_CONF_OPTS += -DCMAKE_EXE_LINKER_FLAGS=-latomic
 endif
 
+ifeq ($(BR2_ARM_CPU_ARMV7M):$(BR2_ARM_CPU_HAS_NEON),y:)
+LIBDE265_CONF_OPTS += -DHAVE_NEON=OFF
+endif
+
 $(eval $(cmake-package))