diff --git a/Ghidra/Features/Base/src/main/java/ghidra/app/plugin/core/marker/MarkerManager.java b/Ghidra/Features/Base/src/main/java/ghidra/app/plugin/core/marker/MarkerManager.java
index 9f7be5042c..426719096f 100644
--- a/Ghidra/Features/Base/src/main/java/ghidra/app/plugin/core/marker/MarkerManager.java
+++ b/Ghidra/Features/Base/src/main/java/ghidra/app/plugin/core/marker/MarkerManager.java
@@ -247,6 +247,9 @@ public class MarkerManager implements MarkerService {
 	void navigateTo(Navigatable navigatable, Program program, int x, int y, int viewHeight,
 			AddressIndexMap addrMap) {
 		MarkerSetCacheEntry entry = markerSetCache.get(program);
+		if (entry == null) {
+			return; // this can happen when no program is open
+		}
 
 		ProgramLocation loc = entry.getProgramLocation(y, viewHeight, addrMap, x);
 		getGoToService();